Factor V Leiden
Sample: Citrated plasma, twice cold centrifuged (store frozen)
Schedule: Daily
Units: % Range 70 - 120
Remarks: Factor V plasma half-life of about 15-36 hours. Factor V activation occurs by both the extrinsic and intrinsic pathways. Factor V deficiency should be considered when a patient with bleeding history has both extended PT and APTT. Low Factor V activity may lead to hematoma formation, post-surgical and post-partum hemorrhage, menorrhagia and hematuria.
